haemolysins

haemolysins
Bacterial exotoxins that lyse erythrocytes.

Dictionary of molecular biology. 2004.

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  • thiol-activated haemolysins — (= oxygen labile haemolysins) Cytolytic bacterial exotoxins that act by binding to cholesterol in cell membranes and forming ring like complexes that act as pores. SH groups of these toxins must be in the reduced state for the toxin to function.… …   Dictionary of molecular biology

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  • haemolytic anaemia — (= hemolytic anemia (USA) ) Anaemia resulting from reduced red cell survival time, either because of an intrinsic defect in the erythrocyte (hereditary spherocytosis or ellipsocytosis, enzyme defects, haemoglobinopathy), or an extrinsic damaging… …   Dictionary of molecular biology

  • perfringolysin O — (= theta toxin; q toxin) Cholesterol binding toxin from Clostridium perfringens. Shares with other thiol activated haemolysins a highly conserved sequence (ECTGLAWEWWR) near the C terminus …   Dictionary of molecular biology

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